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Research Archive

Suit[4]ane / Wenqi (Vince) Liu

Publications – 1191

Suitanes are two-component mechanically interlocked molecules in which one (torso) of the components, with several protruding limbs, is encompassed by another (suit) all-in-one component. We have reported a suit[4]ane, wherein a porphyrin with its four protruding limbs, encompassed by a tricyclic cyclophane, rocks back and forth inside the cyclophane.

Cyclophane-Sustained Ultrastable Porphyrins / Wenqi (Vince) Liu

Publications – 1190

The encapsulation of free-base and zinc porphyrins by a tricyclic cyclophane receptor, XCage, is sustained by subnanomolar binding affinities in water. The resulting complexes demonstrate emergent photophysical enhancements and enjoy unprecedented chemical stabilities, where their D/H exchange, protonation, and solvolysis, under extremely acidic conditions, are completely blocked.

Non-Equilibrium Kinetics & Thermodynamics of Molecular Pumps / Yuanning Feng

Publications – 1189

Non-equilibrium kinetics and thermodynamics associated with transporters and pumps featuring different design principles — i.e., energy and information ratchet mechanisms have been summarized. The limitation of stochastic thermodynamics for catalytic processes has been discussed.

Mechanical-Bond-Induced Exciplex Fluorescence / Amine Garci

Publications – 1188

Our approach to obtaining permanent exciplex photoluminescence begins with the incorporation of anthracene moieties into pyridinium-containing mechanically interlocked molecules (MIMs). The difference in the optical properties of the anthracene-based cyclophanes and the precursor homo[2]catenane are consistent with the role of the mechanical bond in the emergence of the low energy exciplex emission in the catenane.

Ultraporous MOFs / Penghao Li

In Collaboration with – Farha Group / Zhijie Chen

Publications – 1184

The simulation-motivated synthesis of ultraporous metal–organicf rameworks (MOFs) based on metal trinuclear clusters, namely NU-1501-M (M=AlorFe), was realized. Relative to other ultraporous MOFs, NU-1501-Al exhibits a concurrently high gravimetric Brunauer−Emmett−Teller(BET) area of 7310 m2/g-1and av olumetric BET area of 2060 m2/cm-3. The high porosity and surface area of this MOF yielded impressive gravimetric and volumetric storage performances for hydrogen and methane.

Stabilizing Bisradicals with Mechanical Bond / Kang Cai

Publications – 1184

Two new highly charged [2]catenanes have been synthesized and isolated as air-stable singlet bisradicals displaying mixed-valency and multiple redox-states thanks to the unique nano-confinement induced by mechanical bonds in these catenanes.

Single-Crystal Polymers / Qinghui Guo

Publications – 1183

A new principle has been established for preparing single-crystal polycationic polymers utilizing an ultraviolet/sunlight-induced single-crystal-to-single-crystal photopolymerization on a gram-scale in quantitative yield from tricationic monomers possessing self-complementary building blocks.

Tetrazine Box / Qinghui Guo

Publications – 1182

We have made a TetrazineBox, which serves as a toolbox for probing the radical properties and generating efficiently a range of structurally diverse cyclophanes by box-to-box cascade transformations, taking advantage of either reductions or an inverse electron-demand Diels-Alder reaction.

Single-Molecule Conductance of Charged Cyclophanes / Hongliang Chen

Publications – 1181

Intramolecular circuits are built with two-channel charged cyclophanes. An interchannel gating effect and constructive quantum interference act synergistically, leading to a conductance that is 50-fold higher than that of a single-channel control, breaking the single-molecule superposition law.

XCage / Wenqi (Vince) Liu

Publications – 1180

A new tricyclic octacationic cyclophane, XCage, which has a stereoelectronic complementarity towards perylene diimide and shows a picomolar binding affinity in water, has been designed and synthesized.

Redox-Active Macrocycles for Zinc Batteries / Kwan Woo Nam

Publications – 1179

A two-dimensional (2D) conductive metal-organic framework (MOF) with large one-dimensional channels has been developed as a zinc battery cathode. Owing to its unique structure, hydrated Zn2+ ions which are inserted directly into the host structure, Cu3(HHTP)2, allow high-rate performance.

CD-Containing Hybrid Frameworks / Dengke Shen

Publications – 1178

A class of γ-cyclodextrin-containing hybrid frameworks (CD-HFs) has been synthesized, employing γ-cyclodextrin (γ-CD) as the primary building blocks, along with 4-methoxysalicylate (4-MS) anions as the secondary building blocks.

Semi-Artificial Photosynthetic System / Penghao Li

In Collaboration with – Farha Group / Zhijie Chen

Publications – 1177

A prototypical semi-artificial photosynthetic system for efficient carbon dioxide fixation was realized using a modified metal-organic framework NU-1006, which comprises a pre-installed Rh-based electron mediator and also encapsulates coenzyme NAD+/NADH.

Radical-Pairing Interactions in New Hosts / Kang Cai

Publications – 1176

The structure-property relationships between cavity sizes and binding affinities for radical-pairing interactions have been investigated using a series of bisradical dicationic cyclophanes (purple) with different linker units (Ar1 and Ar2 / light pink) to modulate their cavity sizes.

2D Tessellations by Charged Cyclophanes / Yassine Beldjoudi

Publications – 1175

Electron donor-acceptor cyclophanes are programmable building blocks which adopt different 2D tessellations using charge transfer (CT) interactions. The TTF–cyclophane 2D tessellations display dual intra- and intermolecular CT behavior, offering multi-responsive materials.

A molecular dual pump / Yunyan Qiu

Publications – 1172

A molecular dual pump, which consists of two individual pumps linked in a head-to-tail fashion, has been designed and synthesized for the controlled capture and release of a ring via a [2]rotaxane intermediate.

Conductive 2D MOFs for Zinc Batteries / Kwan Woo Nam

Publications – 1170

A redox-active triangular phenanthrenequinone-based macrocycle (PQ-Δ) with a rigid geometry has been developed as a zinc battery cathode. The macrocyclic nature of the PQ-Δ cathode provides a dramatically increased capacity and cyclability compared to that of traditional organic materials.

Cyclophane-Protected NDI Radical / Kang Cai

Publications – 1169

A new strategy has been presented which stabilizes the NDI•– radical anion and modulates its redox properties, by host-guest encapsulation and/or mechanical interlocking with a tetracationic cyclophane, namely, ExBox4+.

Artificial Allomelanin Nanoparticles / Yuanning Feng

In Collaboration with – Gianneschi Group / Xuhao Zhou

Publications – 1168

Artificial allomelanin nanoparticles (AMNPs), analogous to one type of melanin produced by radiation-resistant fungi, have been prepared with well-defined nanostructures. They can be taken up by human epidermal keratinocytes and act as radical scavengers.

A Supramolecular Diamond / Qinghui Guo

Publications – 1167

A unique approach has been established for constructing supramolecular diamond crystals with nanoporous diamondoid superstructures and octahedral shapes, resulting from the hierarchical self-assembly of preorganized hexa-charged molecules quantitatively within seconds under ambient conditions.

Supramolecular Polyknot / Penghao Li

Publications – 1166

A hydrogen-bonded three-dimensional porous supramolecular polyknot with unprecedented self-entangled topology is assembled from a rigid trigonal prismatic triptycene building block with six extended peripheral aryl-carboxyl groups.

Cyclotris(paraquat-p-phenylenes) / Qinghui Guo

Publications – 1165

Redox-active and shape-persistent cyclophanes, namely CTPQT6+ and MCTPQT6+, which are the homologous tricyclic derivatives of the trademark Blue Box from our group, have been synthesized. These derivatives adopt triangular conformations and the 3D packing of MCTPQT6+ results in nanometer-sized channels in the solid state.

Regulated Photodynamic Activity of a Photosensitizer / Indranil Roy

Publications – 1164

A multifunctional synthetic receptor ExBox4+ has been employed to achieve supramolecular photoprotection, lysosomal delivery, and pH-triggered release of a photosensitizer. The use of the ExBox4+ -bound photosensitizer in anticancer treatment using regulated photodynamic therapy is described.

Ligand-Directed Synthesis of Zr-MOFs / Penghao Li

In Collaboration with – Farha Group / Zhijie Chen

Publications – 1163

A series of zirconium-based metal-organic frameworks (Zr-MOFs), i.e. NU160X, with the edge-transitive alb net, was synthesized reticularly from 12-connected hexagonal Zr6 nodes and 6-connected trigonal-prismatic triptycene linkers. These Zr-MOFs exhibit remarkable activities toward the destruction of a nerve agent (Soman) and a nerve agent simulant.

In Situ Photoconversion of Multicolor Luminescence / Huang Wu

Publications – 1160

A photoluminescent supramolecular assembly, the fluorescence of which can be changed efficiently from yellow to blue in an in situ photo-controlled manner, has been prepared in two stages. Employing this assembly, white light emission can be realized expeditiously by a luminescence color-conversion process.

Highly Porous acs-MOFs for Water Sorption / Penghao Li

In Collaboration with – Farha Group / Zhijie Chen

Publications – 1158

A series of non-catenated metal-organic frameworks based on the acs net (acs-MOFs), i.e. NU-1500, was synthesized from trivalent trinuclear metal (Fe3+, Cr3+ and Sc3+) clusters and 6-connected trigonal-prismatic linkers. The highly porous and hydrolytically stable NU-1500-Cr can be activated directly from water and displays an impressive water vapor uptake with a trace of hysteresis.

Interpenetration Isomerism in HOFs / Penghao Li

Publications – 1157

A trigonal prismatic triptycene building block assembles into either a two‐fold interpenetrated acs network (acs‐2 c) or a five‐fold interpenetrated acs network (acs‐5 c) depending upon the crystallization conditions.

Controllable Molecular Encapsulation with Dynamic Host / Huang Wu

Publications – 1156

When a photo-switchable oligo(p-phenylenevinylene) bipyridinium unit (light pink) is incorporated into a tetracationic cyclophane (light blue), it confers upon the cyclophane the ability to direct reversible guest (red and pink) capture and release using thermal and photo stimuli.

Cyclophane for Live-Cell Imaging / Indranil Roy

Publications – 1141

A glowing tetracationic cyclophane (ExTzBox•4Cl) with unity quantum yield has been synthesized and utilized for live-cell imaging. This work, which describes the significance of using box-like cyclophanes for bioimaging, holds promise for the development of multimodal imaging platforms.