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The long-standing challenge of trapping an active native phlorin intermediate in the past six decades has been cracked! A communication entitled “Mechanical trapping of the phlorin intermediate” has been published in CCS Chem by former Postdoctoral Research Fellow Zhichang Liu. Trapping unstable intermediates for elucidating reaction mechanisms in chemistry presents a formidable challenge. There has long

A research article—published by our Foresight Fellows Liang Feng and Yunyan Qiu collaborating with the molecular-machine theorist R. Dean Astumian from the University of Maine—entitled “Active mechanisorption driven by pumping cassettes” has been featured in the latest issues of Nature Chemistry and Angewandte Chemie. This article describes a story of how the team cracked the

A review article entitled “Weak-Bonding Strategies for Achieving Regio- and Site-Selective Transformations” has been published in Chem by Postdoctoral Fellows Yang Jiao and Aspen Chen. Weak bonding interactions, including dynamic covalent and noncovalent bonding interactions, are ubiquitous in many molecular recognition and self-assembly processes in biology. The use of synergistic weak bonding interactions by enzymes