Stoddart Mechanostereochemistry Group





Stoddart Mechanostereochemistry Group



Leah Witus

Postdoctoral Fellow

Hometown: Ann Arbor, MI

Joined group: 2012

Left group: 2015


2007 B.S. in Chemistry, Rice University
Advisor Jeffrey Hartgerink

2012 Ph.D. in Chemistry, UC Berkeley
Advisor Matt Francis

Full CV


Hartlieb, K. J., Witus, L. S., Ferris, D. P., Basuray, A. N., Al-Garadah, M. M., Sarjeant, A. A., Stern, C. L., Nassar, M. S., Stoddart, J. F. Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications. ACS Nano, 2015, 9, 14611470.

Palla, K., Witus, L. S., Mackenzie, K., Netirojjanakul, C., Francis, M. B., Optimization and Expansion of a Site Selective N-Methylpyridinium-4-carboxaldehyde mediated Transamination for Bacterially Expressed Proteins. J. Am. Chem. Soc., 2015, 137, 11231129.

Witus, L. S., Hartlieb, K. J., Wang, Y., Prokofjevs, A., Frasconi, M., Barnes, J. C., Dale, E. J., Fahrenbach, A. C., Stoddart, J. F. Relative contractile motion of the rings in a switchable palindromic [3]rotaxane in aqueous solution driven by radical-pairing interactions. Org. Biomol. Chem., 2014,12, 6089-6093

Witus, L. S., Netirojjanakul, C., Palla, K. S., Muehl, E. M., Weng, C.-H., Iavarone, A. T., Francis, M. B. Site-Specific Protein Transamination Using N-Methylpyridinium-4-carboxaldehyde. J. Am. Chem. Soc., 2013, 135, 1722317229.

Garimella, P. G., Meldrum, T. Witus, L. S., Smith, M., Bajaj, V. S., Wemmer, D. E., Francis, M. B., Pines, A. Hyperpolarized Xenon-Based Molecular Sensors for Label-Free Detection of analytes. J. Am. Chem. Soc., 2014, 136, 164168.

Netirojjanakul, C., Witus, L. S., Behrens, C. R., Weng, C.-H., Iavarone, A. T., Francis, M. B. Synthetically modified Fc domains as building blocks for immunotherapy applications. Chem. Sci. 2013, 4, 266-272.

Witus, L. S., Francis, M. B. Using Synthetically Modified Proteins to Make New Materials. Acc. Chem. Res., 2011, 44, 774783

Witus, L. S., Moore, T., Thuronyi, B. W., Esser-Kahn, A. P., Scheck, R. A., Iavarone, A. T., Francis, M. B. Identification of Highly Reactive Sequences for PLP-Mediated Bioconjugation Using a Combinatorial Peptide Library. J. Am. Chem. Soc. 2010, 132, 16812-16817.

Witus, L. S., Francis, M. B. Site-Specific Protein Bioconjugation Via a Pyridoxal 5-Phosphate-Mediated N-Terminal Transamination Reaction. Current Protocols in Chemical Biology. 2010, 3, 1-10.

Tsyboulski, D. A., Bakota, E. L., Witus, L. S., Rocha, J.-D. R., Hartgerink, J. D., Weisman, R. B. Self-Assembling Peptide Coatings Designed for Highly Luminescent Suspension of Single-Walled Carbon Nanotubes. J. Am. Chem. Soc. 2008, 130, 1713417140.

Witus, L. S., Rocha, J.-D. R., Yuwono, V. M., Paramanov, S. E., Weisman, R. B., Hartgerink, J. D. Peptides that Non-covalently Functionalize Single-Walled Carbon Nanotubes to Give Controlled Solubility Characteristics. J. Mater. Chem. 2007, 17, 1909-1915.


Outside of doing science, I like to bake bacon-related desserts.


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