Stoddart Mechanostereochemistry Group





Stoddart Mechanostereochemistry Group



Zhixue Zhu

Postdoctoral Fellow

Hometown: China

Joined group: 2009

Left group: 2012


University of Reading, UK, PhD, 1999-2003
Supervisor: Prof. Howard M. Colquhoun

Chengdu Institute of Organic Chemistry, The Chinese Academy of Sciences, MSc, 1992-1995.
Supervisor: Prof. Xianmo Deng

Sichuan University, China, BSc 1988-1992


H. M. Colquhoun, B. Greenland, Z. X. Zhu, J. Shaw, C. J. Cardin, S. Burattini, J. Elliott, S. Basu, T. Gasa, J. F. Stoddart, A general synthesis of macrocyclic pi-electron-acceptor systems, Org. Lett., 2009, 11, 5238.

H. M. Colquhoun, Z. X. Zhu, D. J. Williams, M. G. B. Drew, C. J. Cardin, T. B. Marder, A. G. Crawford, Macrocyclic aromatic ether-imide-sulfones: Versatile -acceptor host-molecules with extreme thermo-chemical stability, Chem. Eur. J., 2009, in press.

H. M. Colquhoun, Z. X. Zhu, C. J. Cardin, M. G. B. Drew , Y. Gan, Recognition of sequence-information in synthetic copolymer chains by a conformationally-constrained tweezer molecule, Faraday Discuss., 2009, 143, 205.

Z. X. Zhu, N. M. Walsby, H. M. Colquhoun, D. Thompsett, E. Petrucco, Microblock ionomers: A new concept in high temperature, swelling-resistant membranes for PEM fuel cells, Fuel Cells, 2009, 9, 305-317

H. M. Colquhoun, C. T. Powell, Z. X. Zhu, C. J. Cardin, Y. Gan, P. Tootell, P. S. W. Tsang, N. M. Boag, Enantiospecific assembly of a homochiral, hexanuclear palladium complex, Eur. J. Inorg. Chem., 2009, 999-1002.

H. M. Colquhoun, Z. X. Zhu, C. J. Cardin, Y. Gan, M. G. B. Drew, Sterically-Controlled Recognition of Macromolecular Sequence Information by Molecular Tweezers, J. Am. Chem. Soc., 2007, 129(51), 16163 - 16174..

H. M. Colquhoun, Z. X. Zhu, C. C. Dudman, Enthalpy-Driven Ring-Opening Polymerization of Highly Strained Macrocyclic Biaryl-Ether-Ketones, Macromolecules, 2005, 38(25), 10421-10428.

H. M. Colquhoun, Z. X. Zhu, C. C. Dudman, C. A. O'Mahoney, D. J. Williams, M. G. B. Drew, Synthesis of Strained Macrocyclic Biaryls for Enthalpy-Driven Ring-Opening Polymerization, Macromolecules, 2005, 38(25), 10413-10420.

H. M. Colquhoun, Z. X. Zhu, C. J. Cardin, Y. Gan, Principles of sequence-recognition in aromatic polyimides, Chem. Commun., 2004, 2650-2652.

H. M. Colquhoun, Z. X. Zhu, Recognition of Polyimide Sequence Information by a Molecular Tweezer, Angew. Chem. Int. Ed., 2004, 43(38), 5040-5045.

H. M. Colquhoun*, M. G. Zolotukhin, Z. X. Zhu, P. Hodge, D. J. Williams*, Spontaneous Ring-Opening Polymerization of Macrocyclic Aromatic Thioether Ketones under Transient High-Temperature Conditions, Macromol. Rapid Commun., 2004, 25(7), 808-811.

M. G. Zolotukhin, S. Formine, H. M. Colquhoun, Z. X. Zhu, M. G. B. Drew, R. H. Olley, R. A. Fairman, D. J. Williams, Rapid, Uncatalyzed Ring-Opening Polymerization of Individual Macrocyclic Poly(arylene thioether ketone)s under Dynamic Heating Conditions, Macromolecules, 2004, 37(6), 2041-2053.

H. M. Colquhoun, Z. X. Zhu, D. J. Williams, Extreme Complementarity in a Macrocycle-Tweezer Complex, Org. Lett., 2003, 5 (23), 4353-4356.

H. M. Colquhoun, P. L. Aldred, Z. X. Zhu, D. J. Williams, First Structural Analysis of a Naphthalene-Based Poly(ether ketone): Crystal and Molecular Simulation from X-ray Powder Data and Diffraction Modeling, Macromolecules, 2003, 36(17), 6416-6421.

H. M. Colquhoun, D. J. Williams, Z. X. Zhu, Macrocyclic Aromatic Ether-Imide-Sulfones: Versatile Supramolecular Receptors with Extreme Thermochemical and Oxidative Stability, J. Am. Chem. Soc., 2002, 124(45), 13346-13347.

H. M. Colquhoun, Z. X. Zhu, D. J. Williams, Synthesis and ring-expanding oligomerization of an extremely strained macrocyclic aromatic ether-sulfone, Org. Lett., 2001, 3 (25), 4031-4034.


H. M. Colquhoun, Z. X. Zhu, D. Thompsett, N. M. Walsby, Ion-conducting membranes, WO 2007144633 A1.

H. M. Colquhoun, Z. X. Zhu, W. A. Mortimore, M. P. Hogarth, N. M. Walsby, Ion-conducting polymers and membranes comprising them, WO 2005068536 A1.


I was born in Chongqing (Sichaun Province) in China. After studying at Sichuan University, majoring in Polymer Science, I pursued my masters degree in the field of biodegradable polymers, supervised by Prof. Xianmo Deng. Then I had a four-year industrial position (R&D) at the largest polyester fibre manufacturer in China. I moved to the UK in 1999 to pursue my PhD degree, supervised by Prof. Howard M. Colquhoun, initially at Salford University in Manchester, and then moving with him to the University of Reading (near London) in 2000. I really benefited from his help and encouragement over the past ten years. I enjoyed my life in Reading, being very happy in the family (my wife and I now have a son and daughter) and the science. Motivated by the amazing science and leadership of Professor Stoddart in molecular nanoscience, I was very pleased to be able to join his group to build my knowledge in this tremendously exciting area. In my limited free time, I work to keep myself fit and I spend time with my family. I especially enjoy playing with my two lovely children.


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